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Peptide record

TPDB24380

Antibacterial Toxicity modified_plain modified
8 amino acids
Basic Information
3D PDB MODEL
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TPDB24380
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 8-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
PXKLSLHL
Physicochemical Analysis
C38H66N10O9
ARNDCEQGIMFTWYV
L
807.00
10.10
2
0
3
+1
0.85
0.237
146.25
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
3
L
1
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 3 K: 1 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C38H66N10O9
807.00
10.10
+1
0.85
0.237
Evidence Records 6 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
0% Hemolysis | 256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
The effect of halogenation on the antimicrobial activity, antibiofilm activity, cytotoxicity and proteolytic stability of the antimicrobial peptide Jelleine-I. | Peptides | 2018
Evidence 2 Activity

Activity

10% Killing
Toxicity
256 µM
Cytotoxic
10% Killing | 256 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
The effect of halogenation on the antimicrobial activity, antibiofilm activity, cytotoxicity and proteolytic stability of the antimicrobial peptide Jelleine-I. | Peptides | 2018
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
0% Hemolysis | 256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
The effect of halogenation on the antimicrobial activity, antibiofilm activity, cytotoxicity and proteolytic stability of the antimicrobial peptide Jelleine-I. | Peptides | 2018
Evidence 4 Activity

Activity

<10% Killing
Toxicity
256 µM
Cytotoxic
<10% Killing | 256 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
The effect of halogenation on the antimicrobial activity, antibiofilm activity, cytotoxicity and proteolytic stability of the antimicrobial peptide Jelleine-I. | Peptides | 2018
Evidence 5 Activity

Activity

<5% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
<5% Hemolysis | 256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
The effect of halogenation on the antimicrobial activity, antibiofilm activity, cytotoxicity and proteolytic stability of the antimicrobial peptide Jelleine-I. | Peptides | 2018
Evidence 6 Activity

Activity

10% Killing
Toxicity
256 µM
Cytotoxic
10% Killing | 256 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
The effect of halogenation on the antimicrobial activity, antibiofilm activity, cytotoxicity and proteolytic stability of the antimicrobial peptide Jelleine-I. | Peptides | 2018