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Peptide record

TPDB24362

Antibacterial Anticancer Toxicity standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB24362
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0
standard
No
A 5-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia and CancerPPD 2.0, with an available 3D structural model.
Sequence
PYGFV
Physicochemical Analysis
C30H39N5O7
ARNDCEQHILKMSTW
GFPYV
581.67
5.94
0
0
3
-0
-1.54
0.740
58.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
1490
256.16
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
1
F
1
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
5
C30H39N5O7
581.67
5.94
-0
-1.54
0.740
Evidence Records 3 records
Evidence 1 Activity

Activity

73.49% Cell death
Toxicity
100 µg/mL
Cytotoxic
73.49% Cell death | 100 | µg/mL | target cell: Human skin fibroblasts

Target

Human skin fibroblasts

Source & Reference

NA
DBAASP
Structure-activity relationship studies of Longicalcynin A analogues, as anticancer cyclopeptides. | Chem Biol Interact | 2020
Evidence 2 Activity

Activity

31.99% Cell death
Toxicity
100 µg/mL
Cytotoxic
31.99% Cell death | 100 | µg/mL | target cell: Human skin fibroblasts

Target

Human skin fibroblasts

Source & Reference

NA
DBAASP
Structure-activity relationship studies of Longicalcynin A analogues, as anticancer cyclopeptides. | Chem Biol Interact | 2020
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Chem Biol Interact. 2020 Jan 5 315:108914.