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Peptide record

TPDB24330

Antibacterial Antiparasitic Hemolysis Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB24330
Antibacterial Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia dbAMP 3.0 HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antiparasitic, Hemolysis, and other sources) peptide sequence curated from Peptipedia, dbAMP 3.0, HemoPI, and other sources, with an available 3D structural model.
Sequence
PRRRRSSSRP
Physicochemical Analysis
C49H91N25O14
ANDCEQGHILKMFTWYV
R
1254.42
13.00
5
0
0
+5
5.34
-2.810
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
3
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
2
P
3
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 3 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C49H91N25O14
1254.42
13.00
+5
5.34
-2.810
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Leishmanicidal activity of synthetic antimicrobial peptides in an infection model with human dendritic cells. | Peptides | 2011
Evidence 2 Activity

Activity

50% Cell death
Toxicity
77.08±0.83 µg/mL
Cytotoxic
50% Cell death | 77.08±0.83 | µg/mL | target cell: Human dendritic cells

Target

Human dendritic cells

Source & Reference

NA
DBAASP
Leishmanicidal activity of synthetic antimicrobial peptides in an infection model with human dendritic cells. | Peptides | 2011
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis