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Peptide record

TPDB24325

Antibacterial Anticancer Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB24325
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 7-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
PRPRPRP
Physicochemical Analysis
C38H66N16O8
ANDCEQGHILKMFSTWYV
P
875.04
12.70
3
0
0
+3
4.23
-2.843
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
4
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 4 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C38H66N16O8
875.04
12.70
+3
4.23
-2.843
Evidence Records 4 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>512 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | >512 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Short proline-rich lipopeptide potentiates minocycline and rifampicin against multidrug- and extensively drug-resistant Pseudomonas aeruginosa. | Antimicrob Agents Chemother | 2018
Evidence 2 Activity

Activity

4.6±0.2% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
4.6±0.2% Hemolysis | 512 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Short proline-rich lipopeptide potentiates minocycline and rifampicin against multidrug- and extensively drug-resistant Pseudomonas aeruginosa. | Antimicrob Agents Chemother | 2018
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Short proline-rich lipopeptide potentiates minocycline and rifampicin against multidrug- and extensively drug-resistant Pseudomonas aeruginosa. | Antimicrob Agents Chemother | 2018
Evidence 4 Activity

Activity

5% Hemolysis
Toxicity
16 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 16 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Short proline-rich lipopeptide potentiates minocycline and rifampicin against multidrug- and extensively drug-resistant Pseudomonas aeruginosa. | Antimicrob Agents Chemother | 2018