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Peptide record

TPDB24307

Antibacterial Antifungal Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB24307
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
PMKKLFKLLARIAVKIPVW
Physicochemical Analysis
C111H187N27O20S1
NDCEQGHSTY
K
2251.93
11.80
5
0
12
+5
-0.04
0.679
143.68
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
5500
244.23
0
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
3
L
4
K
1
M
1
F
2
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 3 K: 4 M: 1 F: 1 P: 2 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
19
C111H187N27O20S1
2251.93
11.80
+5
-0.04
0.679
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Toxicity
111.1±27.2 µM
Cytotoxic
IC50 | 111.1±27.2 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
EcDBS1R6: A novel cationic antimicrobial peptide derived from a signal peptide sequence. | Biochim Biophys Acta | 2020