Back to search

Peptide record

TPDB24294

ATN-161 Antibacterial Antiviral Tumor-homing Peptides standard
5 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB24294
ATN-161
Antibacterial Antiviral Tumor-homing Peptides
Anti-infective peptides Cancer-related peptides
Peptipedia dbAMP 3.0 DRAMP DRAVP 2.0 TumorHoPe2.0
standard
No
A 5-aa standard natural multi-activity (Antibacterial, Antiviral, and Tumor-homing Peptides) peptide sequence curated from Peptipedia, dbAMP 3.0, DRAMP, and other sources, with an available 3D structural model.
C-terminal: amide group (-NH2) N-terminal: N-acetyl group
Sequence
PHSCN
Physicochemical Analysis
C21H32N8O8S1
ARDEQGILKMFTWYV
NCHPS
556.59
7.15
1
0
0
+0
1.72
-1.320
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
3
Residue Composition
number
0
A
0
R
1
N
0
D
1
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C21H32N8O8S1
556.59
7.15
+0
1.72
-1.320
amide group (-NH2)
NGR, APRPG, RGD
N-acetyl group
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, endothelial cell
Homing
Melanoma cancer
α5β1

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptide PHSCNK as an integrin α5β1 antagonist targets stealth liposomes to integrin-overexpressing melanoma
2012
Wenbing Dai et al. Nanomedicine. 2012 Oct 8(7):1152-61.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
murine melanoma cells B16F10 , human breast cancer cell MDA-MB-231
Male C57BL/6 mice (6 to 8 weeks old, body weight of 18 to 22 g)
DOX(doxorubicin)-loaded PEGylated liposomes
Additional Detail Fields 3 fields
DOX(doxorubicin)-loaded PEGylated liposomes
murine melanoma cells B16F10 , human breast cancer cell MDA-MB-231
Male C57BL/6 mice (6 to 8 weeks old, body weight of 18 to 22 g)