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Peptide record

TPDB24257

Antibacterial standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB24257
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 22-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
PESKAIKNLLKAVSKERSKRSP
Physicochemical Analysis
C107H192N34O32
DCQGHMFTWY
K
2466.91
11.08
7
2
6
+5
10.75
-1.159
75.45
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
5
Residue Composition
number
2
A
2
R
1
N
0
D
0
C
2
E
0
Q
0
G
0
H
1
I
2
L
5
K
0
M
0
F
2
P
4
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 2 N: 1 D: 0 C: 0 E: 2 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 5 M: 0 F: 0 P: 2 S: 4 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
22
C107H192N34O32
2466.91
11.08
+5
10.75
-1.159
Evidence Records 1 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

alamarBlue analysis: P9 reduced the viability of A. baumannii, P. aeruginosa, E. cloacae, S. typhi, N. gonorrhoeae strains FA1090 and H041, E. coli clinical isolate FI-4531 that expresses mcr-1, colistin-resistant K. pneumoniae clinical isolates, E. faecium, but not S.aureus at 5.6 uM in Kph buffer + 1% TSB (low salt media). This activity is lost against in RPMI medium even at 50 uM. Salt-sensitive (RPMI with physiological levels of salts).