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Peptide record

TPDB24227

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB24227
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia, HemoPI, Hemolytic2, and other sources, with an available 3D structural model.
Sequence
NWKGIAAMAKKLL
Physicochemical Analysis
C67H114N18O15S1
RDCEQHFPSTYV
AK
1443.81
10.84
3
0
8
+3
-0.62
0.223
113.08
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
5500
380.94
1
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
3
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 3 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C67H114N18O15S1
1443.81
10.84
+3
-0.62
0.223
Evidence Records 2 records
Evidence 1 Activity

Activity

24% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
24% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of a novel membrane-destabilizing peptide selectively acting on acidic liposomes. | Biosci Biotechnol Biochem | 2000
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis