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Peptide record

TPDB24222

Antibacterial standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB24222
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 12-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
NYWKKGKWTIGS
Physicochemical Analysis
C70H102N18O17
ARDCEQHLMFPV
K
1467.69
10.46
3
0
4
+3
-1.27
-1.342
32.50
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
12490
851.00
4
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
0
L
3
K
0
M
0
F
0
P
1
S
1
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 0 K: 3 M: 0 F: 0 P: 0 S: 1 T: 1 W: 2 Y: 1 V: 0
Chemical Descriptors
12
C70H102N18O17
1467.69
10.46
+3
-1.27
-1.342
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

Enterobacter cloacae LMG02783

Source & Reference

NA

Other

Active against Gram- E. cloacae LMG02783 (MIC 1 ug/ml), E. coli ATCC25922 (MIC 2 ug/m), P. aeruginosa PAO1 (MIC 2 ug/ml), K. pneumoniae LMG20218
Evidence 2 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

Pseudomonas aeruginosa PAO1

Source & Reference

NA

Other

Active against Gram- E. cloacae LMG02783 (MIC 1 ug/ml), E. coli ATCC25922 (MIC 2 ug/m), P. aeruginosa PAO1 (MIC 2 ug/ml), K. pneumoniae LMG20218 (MIC 2 ug/ml), P. aeruginosa LMG6395 (MIC 4 ug/ml), A. baumannii
Evidence 3 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

Klebsiella pneumoniae LMG20218

Source & Reference

NA

Other

LMG02783 (MIC 1 ug/ml), E. coli ATCC25922 (MIC 2 ug/m), P. aeruginosa PAO1 (MIC 2 ug/ml), K. pneumoniae LMG20218 (MIC 2 ug/ml), P. aeruginosa LMG6395 (MIC 4 ug/ml), A. baumannii ATCC17978 (MIC 16 ug/ml), not inhibito
Evidence 4 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Pseudomonas aeruginosa LMG6395

Source & Reference

NA

Other

922 (MIC 2 ug/m), P. aeruginosa PAO1 (MIC 2 ug/ml), K. pneumoniae LMG20218 (MIC 2 ug/ml), P. aeruginosa LMG6395 (MIC 4 ug/ml), A. baumannii ATCC17978 (MIC 16 ug/ml), not inhibitory till 64 ug/ml against Gram+ E-faec
Evidence 5 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

A. baumannii ATCC17978

Source & Reference

NA

Other

(MIC 2 ug/ml), K. pneumoniae LMG20218 (MIC 2 ug/ml), P. aeruginosa LMG6395 (MIC 4 ug/ml), A. baumannii ATCC17978 (MIC 16 ug/ml), not inhibitory till 64 ug/ml against Gram+ E-faecium LMG16003 (VRE) (MIC >64 ug/ml), S-a