Peptide record

TPDB24198

Antibacterial Antifungal standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB24198
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 11-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
NVGVLNPPPLV
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C52H87N13O14
ARDCEQHIKMFSTWY
PV
1118.34
6.02
0
0
5
-0
-0.87
0.727
150.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
2
L
0
K
0
M
0
F
3
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
11 reviewed residue count
C52H87N13O14 sequence-only estimate (linear, free termini)
1118.34 sequence-only estimate (linear, free termini)
6.02 sequence-only estimate (linear, free termini)
-0 sequence-only estimate (linear, free termini)
-0.87 sequence-only estimate (linear, free termini)
0.727 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against B. cereus ATCC 12432, B. subtilis ATCC 12434, C. difficile ATCC 9689, MRSA, K. pneumoniae ATCC 13883, P. aeruginosa ATCC 10145, R. fascians ATCC 12975, S. marcescens ATCC 14227, S. aureus ATCC 10390, S. epidermidis ATCC 12228, L. monocytogenes ATCC 23073, B. abortus 544, E. coli VTEC KCTC 12900, F. tularensis, S. enterica serovar Stanley, S. enterica serovar Typhimurium ATCC 14028 NA, S. flexneri ATCC 11836, V. cholerae 2590, Y. pestis 3344, Y. enterocolitica 2840, fungi A. solani MYA-995, F. moniliforme ATCC 10052, F. oxysporum ATCC 12581, H. sativum ATCC 11404. Replaced 2/2019 update 2/2024 GW.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

CAFPdb Antifungipept

Other

Active against B. cereus ATCC 12432, B. subtilis ATCC 12434, C. difficile ATCC 9689, MRSA, K. pneumoniae ATCC 13883, P. aeruginosa ATCC 10145, R. fascians ATCC 12975, S. marcescens ATCC 14227, S. aureus ATCC 10390, S. epidermidis ATCC 12228, L. monocytogenes ATCC 23073, B. abortus 544, E. coli VTEC KCTC 12900, F. tularensis, S. enterica serovar Stanley, S. enterica serovar Typhimurium ATCC 14028 NA, S. flexneri ATCC 11836, V. cholerae 2590, Y. pestis 3344, Y. enterocolitica 2840, fungi A. solani MYA-995, F. moniliforme ATCC 10052, F. oxysporum ATCC 12581, H. sativum ATCC 11404. Replaced 2/2019 update 2/2024 GW.