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Peptide record

TPDB24131

Antibacterial Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB24131
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 8-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
NPSRQERR
Physicochemical Analysis
C40H71N19O14
ADCGHILKMFTWYV
R
1042.12
12.10
3
1
0
+2
6.03
-3.300
0.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
1
E
1
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C40H71N19O14
1042.12
12.10
+2
6.03
-3.300
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Killing
Toxicity
18000 µM
Cytotoxic
<5% Killing | 18000 | µM | target cell: Chicken macrophages HD-11

Target

Chicken macrophages HD-11

Source & Reference

NA
DBAASP
Peptides Affecting the Outer Membrane Lipid Asymmetry System (MlaA-OmpC/F) Reduce Avian Pathogenic Escherichia coli (APEC) Colonization in Chickens. | Appl Environ Microbiol | 2021