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Peptide record

TPDB24077

Antibacterial Antiviral Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB24077
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAMP DRAVP 2.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
NGAICWGPCPTAFRQIGNCGHFKVRCCKIR
Physicochemical Analysis
C144H227N47O35S5
DELMSY
C
3336.98
9.34
6
0
9
+5
1.36
-0.067
55.33
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
5750
172.31
9
Residue Composition
number
2
A
3
R
2
N
0
D
5
C
0
E
1
Q
4
G
1
H
3
I
0
L
2
K
0
M
2
F
2
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 3 N: 2 D: 0 C: 5 E: 0 Q: 1 G: 4 H: 1 I: 3 L: 0 K: 2 M: 0 F: 2 P: 2 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
30
C144H227N47O35S5
3336.98
9.34
+5
1.36
-0.067
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
380 µg/mL
Cytotoxic
50% Cytotoxicity | 380 | µg/mL | target cell: Madin-Darby canine kidney cells

Target

Madin-Darby canine kidney cells

Source & Reference

NA
DBAASP
A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses. | Sci Rep | 2016
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.26911565]Xytotoxicity against Madin-Darby canine kidney cells(TC50=380 µg/ml).

Source & Reference

NA
DRAMP
Sci Rep. 2016 Feb 25 6:22008. ##Nat Commun. 2020 Aug 25 11(1):4252.