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Peptide record

TPDB24071

Antibacterial Antifungal standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB24071
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 29-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
NGKKKRKKPEKLCMKPGACSVIFDASVNE
Physicochemical Analysis
C138H237N41O40S3
QHTWY
K
3206.83
10.18
8
3
8
+5
12.12
-0.859
53.79
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
125
3.90
6
Residue Composition
number
2
A
1
R
2
N
1
D
2
C
2
E
0
Q
2
G
0
H
1
I
1
L
7
K
1
M
1
F
2
P
2
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 1 C: 2 E: 2 Q: 0 G: 2 H: 0 I: 1 L: 1 K: 7 M: 1 F: 1 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
29
C138H237N41O40S3
3206.83
10.18
+5
12.12
-0.859
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against Gram- bacterium A. hydrophila (MIC 10 mg/L). BG-CATH25, obtained after deleting the N-terminal four residues, is more active (MIC 1.25). APD comment: Which is the native form remains to be established by Edman degradation of the purified peptide. Updated 7/2020
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against Gram- bacterium A. hydrophila (MIC 10 mg/L). BG-CATH25, obtained after deleting the N-terminal four residues, is more active (MIC 1.25). APD comment: Which is the native form remains to be established by Edman degradation of the purified peptide. Updated 7/2020