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Peptide record

TPDB24069

Antibacterial Antifungal standard
79 amino acids
Basic Information
3D PDB MODEL
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TPDB24069
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 79-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
NGIECEMCKMSVKIVVPMLGEDTESIKKAVDAECKKEFHSIPFGTQECKKFIDTKLDPIIHELENGTAPSDVCTKLGMC
Physicochemical Analysis
C377H616N96O120S10
RWY
K
8734.21
4.88
12
14
26
-4
30.32
-0.201
76.46
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
375
4.29
18
Residue Composition
number
3
A
0
R
2
N
5
D
6
C
9
E
1
Q
5
G
2
H
7
I
4
L
10
K
4
M
3
F
4
P
4
S
5
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 5 C: 6 E: 9 Q: 1 G: 5 H: 2 I: 7 L: 4 K: 10 M: 4 F: 3 P: 4 S: 4 T: 5 W: 0 Y: 0 V: 5
Chemical Descriptors
79
C377H616N96O120S10
8734.21
4.88
-4
30.32
-0.201
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against Gram-positive and Gram-negative bacteria E. coli, P. aeruginosa, Photorhabdus luminescens, X. nematophila, Y. enterocolitica, B. megaterium and B. thuringiensis. SPP-3 formed pores in liposomes composed of asolectin in a pH-dependent manner displaying maximal activity at pH 4.4.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against Gram-positive and Gram-negative bacteria E. coli, P. aeruginosa, Photorhabdus luminescens, X. nematophila, Y. enterocolitica, B. megaterium and B. thuringiensis. SPP-3 formed pores in liposomes composed of asolectin in a pH-dependent manner displaying maximal activity at pH 4.4.