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Peptide record

TPDB23930

Antibacterial Hemolysis Toxicity standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB23930
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 43-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia, HemoPI, Hemolytic2, and other sources, with an available 3D structural model.
Sequence
MSDFVNAISEAVKAGLSADWVTMGTSIADALAKGADFILGFFN
Physicochemical Analysis
C201H308N48O62S2
RCQHPY
A
4453.06
3.77
2
5
24
-3
0.01
0.640
93.26
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
123.51
8
Residue Composition
number
8
A
0
R
2
N
4
D
0
C
1
E
0
Q
4
G
0
H
3
I
3
L
2
K
2
M
4
F
0
P
4
S
2
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 8 R: 0 N: 2 D: 4 C: 0 E: 1 Q: 0 G: 4 H: 0 I: 3 L: 3 K: 2 M: 2 F: 4 P: 0 S: 4 T: 2 W: 1 Y: 0 V: 3
Chemical Descriptors
43
C201H308N48O62S2
4453.06
3.77
-3
0.01
0.640
Evidence Records 6 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
2630±60 µM
Hemolytic Cytotoxic
50% Hemolysis | 2630±60 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
2370±80 µM
Hemolytic Cytotoxic
50% Hemolysis | 2370±80 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
1980±50 µM
Hemolytic Cytotoxic
50% Hemolysis | 1980±50 | µM | target cell: Guinea pig erythrocytes

Target

Guinea pig erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
1020±40 µM
Hemolytic Cytotoxic
50% Hemolysis | 1020±40 | µM | target cell: Dog erythrocytes

Target

Dog erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
2070±50 µM
Hemolytic Cytotoxic
50% Hemolysis | 2070±50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 6 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis