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Peptide record

TPDB23919

hBD-2 Antibacterial Anticancer Antifungal Antiparasitic Cell-penetrating Peptides standard
64 amino acids
Basic Information
3D PDB MODEL
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TPDB23919
hBD-2
Antibacterial Anticancer Antifungal Antiparasitic Cell-penetrating Peptides
Anti-infective peptides Cancer-related peptides Delivery and barrier-penetrating peptides
Peptipedia CPPsite3.0
standard
No
A 64-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia and CPPsite3.0, with an available 3D structural model.
Sequence
MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP
Physicochemical Analysis
C327H515N81O75S8
NEW
GL
7037.66
9.53
9
1
27
+7
-2.11
0.605
92.81
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
47.67
14
Residue Composition
number
1
A
3
R
0
N
1
D
6
C
0
E
1
Q
8
G
1
H
4
I
8
L
5
K
2
M
6
F
7
P
2
S
3
T
0
W
2
Y
4
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 1 C: 6 E: 0 Q: 1 G: 8 H: 1 I: 4 L: 8 K: 5 M: 2 F: 6 P: 7 S: 2 T: 3 W: 0 Y: 2 V: 4
Chemical Descriptors
64
C327H515N81O75S8
7037.66
9.53
+7
-2.11
0.605
Free
L
Linear
Free
N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Polarized Tonsil Epithelial Cells , Ex-Vivo Infant Tonsil Tissues

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Cytoplasm
Endocytosis
In vitro and ex vivo
CCSTTHHHHHHHHHSSCSTTTTTTCCCCSSSCCSSSCCCSCCCCCCCCSSCBSSSSBCCSCCC
Additional Detail Fields 1 fields
CCSTTHHHHHHHHHSSCSTTTTTTCCCCSSSCCSSSCCCSCCCCCCCCSSCBSSSSBCCSCCC