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Peptide record

TPDB23916

Antibacterial Antifungal standard
131 amino acids
Basic Information
3D PDB MODEL
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TPDB23916
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 131-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
MRVLLLLVSLAAVGNAYNAKVPIQTLPERLDNFPGRGPSFTRPAVVGVQTLPGRVPPQTFPGVIGVGTKPLISPPRPGFTGSTRPFQRPGQYSFTRSNCWARCPGYPNGDSLCCRQYGACCSTSYPVPYKG
Physicochemical Analysis
C631H985N179O173S7
H
P
14071.28
10.16
14
3
45
+11
10.18
-0.189
68.40
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
14815
105.29
41
Residue Composition
number
7
A
11
R
5
N
2
D
6
C
1
E
6
Q
15
G
0
H
3
I
10
L
3
K
1
M
6
F
19
P
9
S
9
T
1
W
6
Y
11
V
Amino Acid Distribution
A: 7 R: 11 N: 5 D: 2 C: 6 E: 1 Q: 6 G: 15 H: 0 I: 3 L: 10 K: 3 M: 1 F: 6 P: 19 S: 9 T: 9 W: 1 Y: 6 V: 11
Chemical Descriptors
131
C631H985N179O173S7
14071.28
10.16
+11
10.18
-0.189
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.63-2.5 µM

Target

A. hydrophila

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram- bacteria P. stutzeri, P. fluorescens, A. hydrophila (MIC 0.63-2.5 uM), Gram+ M. luteus, S. aureus, C. glutamicum, M. lysodeikticus (MIC 0.63-5 uM), and yeast P
Evidence 2 Activity

Activity

MIC
Antibacterial
0.63-5 µM

Target

M. lysodeikticus

Source & Reference

dbAMP

Other

fluorescens, A. hydrophila (MIC 0.63-2.5 uM), Gram+ M. luteus, S. aureus, C. glutamicum, M. lysodeikticus (MIC 0.63-5 uM), and yeast P. pastoris GS115 (MIC 2.5-5 uM). Domain activity: PRD is more active than CRD
Evidence 3 Activity

Activity

MIC
Antibacterial
2.5-5 µM

Target

P. pastoris GS115

Source & Reference

dbAMP

Other

), Gram+ M. luteus, S. aureus, C. glutamicum, M. lysodeikticus (MIC 0.63-5 uM), and yeast P. pastoris GS115 (MIC 2.5-5 uM). Domain activity: PRD is more active than CRD. With the challenge of either Vibrio paraha
Evidence 4 Activity

Activity

MIC
Antifungal
0.63-2.5 µM

Target

A. hydrophila

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram- bacteria P. stutzeri, P. fluorescens, A. hydrophila (MIC 0.63-2.5 uM), Gram+ M. luteus, S. aureus, C. glutamicum, M. lysodeikticus (MIC 0.63-5 uM), and yeast P
Evidence 5 Activity

Activity

MIC
Antifungal
0.63-5 µM

Target

M. lysodeikticus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

fluorescens, A. hydrophila (MIC 0.63-2.5 uM), Gram+ M. luteus, S. aureus, C. glutamicum, M. lysodeikticus (MIC 0.63-5 uM), and yeast P. pastoris GS115 (MIC 2.5-5 uM). Domain activity: PRD is more active than CRD
Evidence 6 Activity

Activity

MIC
Antifungal
2.5-5 µM

Target

P. pastoris GS115

Source & Reference

dbAMP CAFPdb Antifungipept

Other

), Gram+ M. luteus, S. aureus, C. glutamicum, M. lysodeikticus (MIC 0.63-5 uM), and yeast P. pastoris GS115 (MIC 2.5-5 uM). Domain activity: PRD is more active than CRD. With the challenge of either Vibrio paraha