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Peptide record

TPDB23847

Antibacterial Antifungal standard
71 amino acids
Basic Information
3D PDB MODEL
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TPDB23847
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 71-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
MRLSHVCSQSSSKYPAGSCNLMTHDRATSSEHRSASRCDRVIRRFCRSDPASRYWRYPVRGMRHGRCHTDW
Physicochemical Analysis
C346H545N125O102S8
R
8344.39
10.62
19
5
19
+9
16.18
-1.034
34.37
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
15720
188.39
25
Residue Composition
number
4
A
13
R
1
N
4
D
5
C
1
E
1
Q
3
G
5
H
1
I
2
L
1
K
3
M
1
F
3
P
12
S
3
T
2
W
3
Y
3
V
Amino Acid Distribution
A: 4 R: 13 N: 1 D: 4 C: 5 E: 1 Q: 1 G: 3 H: 5 I: 1 L: 2 K: 1 M: 3 F: 1 P: 3 S: 12 T: 3 W: 2 Y: 3 V: 3
Chemical Descriptors
71
C346H545N125O102S8
8344.39
10.62
+9
16.18
-1.034
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
100-200 µg/mL

Target

Enterococcus faecalis

Source & Reference

NA

Other

bacteriostatic against E. faecalis (MIC 100-200 ug/ml) (cf. positive control: vancomycin 62.5 ug/ml). Also inhibited growth of E. coli ,no MIC.
Evidence 2 Activity

Activity

MIC
Antifungal
100-200 µg/mL

Target

Enterococcus faecalis

Source & Reference

Antifungipept

Other

bacteriostatic against E. faecalis (MIC 100-200 ug/ml) (cf. positive control: vancomycin 62.5 ug/ml). Also inhibited growth of E. coli ,no MIC.