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Peptide record

TPDB23792

Antibacterial Antifungal standard
92 amino acids
Basic Information
3D PDB MODEL
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TPDB23792
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse
standard
No
A 92-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and AFP-GFuse, with an available 3D structural model.
Sequence
MQLTSIAIILFAAMGAIANPIAAESDDLLARDAQLSKYGGECSLEHNTCTYRKDGKNHVVSCPSAANLRCKTDRHHCEYDDHHKTVDCQTPV
Physicochemical Analysis
C427H680N128O139S8
W
A
10087.35
6.03
15
12
33
-3
25.39
-0.383
75.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
4845
48.03
28
Residue Composition
number
11
A
4
R
4
N
8
D
6
C
4
E
3
Q
4
G
6
H
5
I
7
L
5
K
2
M
1
F
3
P
6
S
6
T
0
W
3
Y
4
V
Amino Acid Distribution
A: 11 R: 4 N: 4 D: 8 C: 6 E: 4 Q: 3 G: 4 H: 6 I: 5 L: 7 K: 5 M: 2 F: 1 P: 3 S: 6 T: 6 W: 0 Y: 3 V: 4
Chemical Descriptors
92
C427H680N128O139S8
10087.35
6.03
-3
25.39
-0.383
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against S. aureus and C. albicans (agar diffusion assay). MIC assays: S. aureus (MIC 32 ug/ml 3.9 uM) and MRSA (128 ug/ml 15.4 uM). Antibiofilm:bacteria: Inhibited bacterial biofilm formation:S. aureus MRSA (at 2 and 8 ug/ml).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

NA

Other

Active against S. aureus and C. albicans (agar diffusion assay). MIC assays: S. aureus (MIC 32 ug/ml 3.9 uM) and MRSA (128 ug/ml 15.4 uM). Antibiofilm:bacteria: Inhibited bacterial biofilm formation:S. aureus MRSA (at 2 and 8 ug/ml).