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Peptide record

TPDB23603

Anti-inflammatory Antibacterial Antifungal standard
67 amino acids
Basic Information
3D PDB MODEL
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TPDB23603
Anti-inflammatory Antibacterial Antifungal
Anti-infective peptides Immunity and inflammation peptides
Peptipedia Antifungipept
standard
No
A 67-aa standard natural multi-activity (Anti-inflammatory, Antibacterial, and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
MKPQSILVLLVLAVLALHCKENEAASFPWTCASLSGVCRQGVCLPSELYFGSLGCGKGFLCCVSHFG
Physicochemical Analysis
C318H501N81O86S8
D
L
7091.45
7.57
6
3
30
+1
-0.31
0.767
103.28
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7365
103.86
19
Residue Composition
number
5
A
1
R
1
N
0
D
7
C
3
E
2
Q
7
G
2
H
1
I
11
L
3
K
1
M
4
F
3
P
7
S
1
T
1
W
1
Y
6
V
Amino Acid Distribution
A: 5 R: 1 N: 1 D: 0 C: 7 E: 3 Q: 2 G: 7 H: 2 I: 1 L: 11 K: 3 M: 1 F: 4 P: 3 S: 7 T: 1 W: 1 Y: 1 V: 6
Chemical Descriptors
67
C318H501N81O86S8
7091.45
7.57
+1
-0.31
0.767
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
36 µM

Target

A. hydrophila ATCC 7966

Source & Reference

NA

Other

While thioredoxin was not antimicrobial, fusion Trx-Defb1 inhibited the growth of A. hydrophila ATCC 7966 (MIC 36 uM). The bacterial growth in Trx-Defb1-treated group was sharply inhibited by more than 90% c
Evidence 2 Activity

Activity

MIC
Antifungal
36 µM

Target

A. hydrophila ATCC 7966

Source & Reference

Antifungipept

Other

While thioredoxin was not antimicrobial, fusion Trx-Defb1 inhibited the growth of A. hydrophila ATCC 7966 (MIC 36 uM). The bacterial growth in Trx-Defb1-treated group was sharply inhibited by more than 90% c