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Peptide record

TPDB23487

Antibacterial Toxicity standard
61 amino acids
Basic Information
3D PDB MODEL
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TPDB23487
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 61-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
MHHHHHHDDDDKSDYLNNNPLFPRYDIGNVELSTAYRSFANQKAPGRLNQNWALTADYTYR
Physicochemical Analysis
C318H461N97O98S1
C
ND
7242.81
6.31
12
8
21
-1
14.96
-1.275
51.31
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12950
178.80
20
Residue Composition
number
5
A
4
R
7
N
7
D
0
C
1
E
2
Q
2
G
6
H
1
I
5
L
2
K
1
M
2
F
3
P
3
S
3
T
1
W
5
Y
1
V
Amino Acid Distribution
A: 5 R: 4 N: 7 D: 7 C: 0 E: 1 Q: 2 G: 2 H: 6 I: 1 L: 5 K: 2 M: 1 F: 2 P: 3 S: 3 T: 3 W: 1 Y: 5 V: 1
Chemical Descriptors
61
C318H461N97O98S1
7242.81
6.31
-1
14.96
-1.275
Evidence Records 4 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Expression, purification and characterization of a recombinant antimicrobial peptide Hispidalin in Pichia pastoris. | Protein Expr Purif | 2019
Evidence 2 Activity

Activity

<2% Hemolysis
Toxicity
300 µg/mL
Hemolytic Cytotoxic
<2% Hemolysis | 300 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Expression, purification and characterization of a recombinant antimicrobial peptide Hispidalin in Pichia pastoris. | Protein Expr Purif | 2019
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 100 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Expression, purification and characterization of a recombinant antimicrobial peptide Hispidalin in Pichia pastoris. | Protein Expr Purif | 2019
Evidence 4 Activity

Activity

<2% Hemolysis
Toxicity
300 µg/mL
Hemolytic Cytotoxic
<2% Hemolysis | 300 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Expression, purification and characterization of a recombinant antimicrobial peptide Hispidalin in Pichia pastoris. | Protein Expr Purif | 2019