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Peptide record

TPDB23428

Antibacterial Antifungal standard
63 amino acids
Basic Information
3D PDB MODEL
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TPDB23428
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 63-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
MFAMKTKAALAIWCPGYSETQINATQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNRPLLKQQ
Physicochemical Analysis
C327H543N101O86S5
DH
K
7425.83
11.54
14
2
24
+12
11.09
-0.716
68.25
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12615
169.88
20
Residue Composition
number
6
A
6
R
3
N
0
D
2
C
2
E
7
Q
2
G
0
H
2
I
6
L
8
K
3
M
2
F
2
P
2
S
5
T
2
W
1
Y
2
V
Amino Acid Distribution
A: 6 R: 6 N: 3 D: 0 C: 2 E: 2 Q: 7 G: 2 H: 0 I: 2 L: 6 K: 8 M: 3 F: 2 P: 2 S: 2 T: 5 W: 2 Y: 1 V: 2
Chemical Descriptors
63
C327H543N101O86S5
7425.83
11.54
+12
11.09
-0.716
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Compared to the long form, which was also reproted to be antimicrobial mainly against Gram- bacteria ( Sonesson A et al., 2011 ), this short form TSLP (sfTSLP) exhibited a markedly stronger antibacterial activity against B. cereus, E. coli, E. faecalis, S. mitis, S. epidermidis, and C. albicans. (Incubate 2 h followed by plating count).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Compared to the long form, which was also reproted to be antimicrobial mainly against Gram- bacteria ( Sonesson A et al., 2011 ), this short form TSLP (sfTSLP) exhibited a markedly stronger antibacterial activity against B. cereus, E. coli, E. faecalis, S. mitis, S. epidermidis, and C. albicans. (Incubate 2 h followed by plating count).