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Peptide record

TPDB23404

Antibacterial Antifungal standard
140 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB23404
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 140-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
Physicochemical Analysis
C627H1012N166O216S4
RCW
AV
14460.16
4.46
16
24
54
-9
56.94
-0.403
69.64
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5960
41.22
27
Residue Composition
number
19
A
0
R
3
N
6
D
0
C
18
E
6
Q
18
G
1
H
2
I
4
L
15
K
4
M
2
F
5
P
4
S
10
T
0
W
4
Y
19
V
Amino Acid Distribution
A: 19 R: 0 N: 3 D: 6 C: 0 E: 18 Q: 6 G: 18 H: 1 I: 2 L: 4 K: 15 M: 4 F: 2 P: 5 S: 4 T: 10 W: 0 Y: 4 V: 19
Chemical Descriptors
140
C627H1012N166O216S4
14460.16
4.46
-9
56.94
-0.403
Evidence Records 24 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.2 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against bacteria E. coli (MIC 0.2 uM), P. aeruginosa (MIC 0.2 uM), S. aureus (MIC 0.2 uM), S. epidermidis (MIC 0.2 uM), yeast C
Evidence 2 Activity

Activity

MIC
Antibacterial
0.2 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP

Other

Active against bacteria E. coli (MIC 0.2 uM), P. aeruginosa (MIC 0.2 uM), S. aureus (MIC 0.2 uM), S. epidermidis (MIC 0.2 uM), yeast C. albicans (MIC 0.4 uM), C.
Evidence 3 Activity

Activity

MIC
Antibacterial
0.2 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Active against bacteria E. coli (MIC 0.2 uM), P. aeruginosa (MIC 0.2 uM), S. aureus (MIC 0.2 uM), S. epidermidis (MIC 0.2 uM), yeast C. albicans (MIC 0.4 uM), C. tropicalis (MIC 0.4 uM),
Evidence 4 Activity

Activity

MIC
Antibacterial
0.2 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP

Other

gainst bacteria E. coli (MIC 0.2 uM), P. aeruginosa (MIC 0.2 uM), S. aureus (MIC 0.2 uM), S. epidermidis (MIC 0.2 uM), yeast C. albicans (MIC 0.4 uM), C. tropicalis (MIC 0.4 uM), F. neoformans (MIC 0.8 uM),
Evidence 5 Activity

Activity

MIC
Antibacterial
0.4 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

), P. aeruginosa (MIC 0.2 uM), S. aureus (MIC 0.2 uM), S. epidermidis (MIC 0.2 uM), yeast C. albicans (MIC 0.4 uM), C. tropicalis (MIC 0.4 uM), F. neoformans (MIC 0.8 uM), mold A. flavus (MIC 0.8 uM), A.
Evidence 6 Activity

Activity

MIC
Antibacterial
0.4 µM

Target

C. tropicalis

Source & Reference

dbAMP

Other

uM), S. aureus (MIC 0.2 uM), S. epidermidis (MIC 0.2 uM), yeast C. albicans (MIC 0.4 uM), C. tropicalis (MIC 0.4 uM), F. neoformans (MIC 0.8 uM), mold A. flavus (MIC 0.8 uM), A. fumigatus (MIC 1.6 uM), A. p
Evidence 7 Activity

Activity

MIC
Antibacterial
0.8 µM

Target

F. neoformans

Source & Reference

dbAMP

Other

S. epidermidis (MIC 0.2 uM), yeast C. albicans (MIC 0.4 uM), C. tropicalis (MIC 0.4 uM), F. neoformans (MIC 0.8 uM), mold A. flavus (MIC 0.8 uM), A. fumigatus (MIC 1.6 uM), A. parasiticus (MIC 1.6 uM), R.
Evidence 8 Activity

Activity

MIC
Antibacterial
0.8 µM

Target

A. flavus

Source & Reference

dbAMP

Other

st C. albicans (MIC 0.4 uM), C. tropicalis (MIC 0.4 uM), F. neoformans (MIC 0.8 uM), mold A. flavus (MIC 0.8 uM), A. fumigatus (MIC 1.6 uM), A. parasiticus (MIC 1.6 uM), R. solani (MIC 3.2 uM), and T. h
Evidence 9 Activity

Activity

MIC
Antibacterial
1.6 µM

Target

A. fumigatus

Source & Reference

dbAMP

Other

uM), C. tropicalis (MIC 0.4 uM), F. neoformans (MIC 0.8 uM), mold A. flavus (MIC 0.8 uM), A. fumigatus (MIC 1.6 uM), A. parasiticus (MIC 1.6 uM), R. solani (MIC 3.2 uM), and T. harzianum (MIC 3.2 uM).
Evidence 10 Activity

Activity

MIC
Antibacterial
1.6 µM

Target

A. parasiticus

Source & Reference

dbAMP

Other

uM), F. neoformans (MIC 0.8 uM), mold A. flavus (MIC 0.8 uM), A. fumigatus (MIC 1.6 uM), A. parasiticus (MIC 1.6 uM), R. solani (MIC 3.2 uM), and T. harzianum (MIC 3.2 uM).
Evidence 11 Activity

Activity

MIC
Antibacterial
3.2 µM

Target

R. solani

Source & Reference

dbAMP

Other

uM), mold A. flavus (MIC 0.8 uM), A. fumigatus (MIC 1.6 uM), A. parasiticus (MIC 1.6 uM), R. solani (MIC 3.2 uM), and T. harzianum (MIC 3.2 uM).
Evidence 12 Activity

Activity

MIC
Antibacterial
3.2 µM

Target

T. harzianum

Source & Reference

dbAMP

Other

uM), A. fumigatus (MIC 1.6 uM), A. parasiticus (MIC 1.6 uM), R. solani (MIC 3.2 uM), and T. harzianum (MIC 3.2 uM).
Evidence 13 Activity

Activity

MIC
Antifungal
0.2 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against bacteria E. coli (MIC 0.2 uM), P. aeruginosa (MIC 0.2 uM), S. aureus (MIC 0.2 uM), S. epidermidis (MIC 0.2 uM), yeast C
Evidence 14 Activity

Activity

MIC
Antifungal
0.2 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against bacteria E. coli (MIC 0.2 uM), P. aeruginosa (MIC 0.2 uM), S. aureus (MIC 0.2 uM), S. epidermidis (MIC 0.2 uM), yeast C. albicans (MIC 0.4 uM), C.
Evidence 15 Activity

Activity

MIC
Antifungal
0.2 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against bacteria E. coli (MIC 0.2 uM), P. aeruginosa (MIC 0.2 uM), S. aureus (MIC 0.2 uM), S. epidermidis (MIC 0.2 uM), yeast C. albicans (MIC 0.4 uM), C. tropicalis (MIC 0.4 uM),
Evidence 16 Activity

Activity

MIC
Antifungal
0.2 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

gainst bacteria E. coli (MIC 0.2 uM), P. aeruginosa (MIC 0.2 uM), S. aureus (MIC 0.2 uM), S. epidermidis (MIC 0.2 uM), yeast C. albicans (MIC 0.4 uM), C. tropicalis (MIC 0.4 uM), F. neoformans (MIC 0.8 uM),
Evidence 17 Activity

Activity

MIC
Antifungal
0.4 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

), P. aeruginosa (MIC 0.2 uM), S. aureus (MIC 0.2 uM), S. epidermidis (MIC 0.2 uM), yeast C. albicans (MIC 0.4 uM), C. tropicalis (MIC 0.4 uM), F. neoformans (MIC 0.8 uM), mold A. flavus (MIC 0.8 uM), A.
Evidence 18 Activity

Activity

MIC
Antifungal
0.4 µM

Target

C. tropicalis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

uM), S. aureus (MIC 0.2 uM), S. epidermidis (MIC 0.2 uM), yeast C. albicans (MIC 0.4 uM), C. tropicalis (MIC 0.4 uM), F. neoformans (MIC 0.8 uM), mold A. flavus (MIC 0.8 uM), A. fumigatus (MIC 1.6 uM), A. p
Evidence 19 Activity

Activity

MIC
Antifungal
0.8 µM

Target

F. neoformans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

S. epidermidis (MIC 0.2 uM), yeast C. albicans (MIC 0.4 uM), C. tropicalis (MIC 0.4 uM), F. neoformans (MIC 0.8 uM), mold A. flavus (MIC 0.8 uM), A. fumigatus (MIC 1.6 uM), A. parasiticus (MIC 1.6 uM), R.
Evidence 20 Activity

Activity

MIC
Antifungal
0.8 µM

Target

A. flavus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

st C. albicans (MIC 0.4 uM), C. tropicalis (MIC 0.4 uM), F. neoformans (MIC 0.8 uM), mold A. flavus (MIC 0.8 uM), A. fumigatus (MIC 1.6 uM), A. parasiticus (MIC 1.6 uM), R. solani (MIC 3.2 uM), and T. h
Evidence 21 Activity

Activity

MIC
Antifungal
1.6 µM

Target

A. fumigatus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

uM), C. tropicalis (MIC 0.4 uM), F. neoformans (MIC 0.8 uM), mold A. flavus (MIC 0.8 uM), A. fumigatus (MIC 1.6 uM), A. parasiticus (MIC 1.6 uM), R. solani (MIC 3.2 uM), and T. harzianum (MIC 3.2 uM).
Evidence 22 Activity

Activity

MIC
Antifungal
1.6 µM

Target

A. parasiticus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

uM), F. neoformans (MIC 0.8 uM), mold A. flavus (MIC 0.8 uM), A. fumigatus (MIC 1.6 uM), A. parasiticus (MIC 1.6 uM), R. solani (MIC 3.2 uM), and T. harzianum (MIC 3.2 uM).
Evidence 23 Activity

Activity

MIC
Antifungal
3.2 µM

Target

R. solani

Source & Reference

dbAMP CAFPdb Antifungipept

Other

uM), mold A. flavus (MIC 0.8 uM), A. fumigatus (MIC 1.6 uM), A. parasiticus (MIC 1.6 uM), R. solani (MIC 3.2 uM), and T. harzianum (MIC 3.2 uM).
Evidence 24 Activity

Activity

MIC
Antifungal
3.2 µM

Target

T. harzianum

Source & Reference

dbAMP CAFPdb Antifungipept

Other

uM), A. fumigatus (MIC 1.6 uM), A. parasiticus (MIC 1.6 uM), R. solani (MIC 3.2 uM), and T. harzianum (MIC 3.2 uM).