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Peptide record

TPDB23399

Antibacterial Antifungal standard
97 amino acids
Basic Information
3D PDB MODEL
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TPDB23399
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 97-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
MDTMIDSLNKDMWAETTAKADGYKEYTINRQHKRIDKTTLGLFLDPEEGDSVTVQINDTLDDKDPLKNICRAEFKLDPTNTKVIGIDLDGDIVERKS
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C477H771N129O162S4
D
11033.38
4.38
15
21
32
-7
2.56
-0.760
80.41
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
8480
0.77
23
Residue Composition
number
4
A
4
R
5
N
15
D
1
C
6
E
2
Q
5
G
1
H
8
I
8
L
10
K
3
M
2
F
3
P
3
S
10
T
1
W
2
Y
4
V
Amino Acid Distribution
A: 4 R: 4 N: 5 D: 15 C: 1 E: 6 Q: 2 G: 5 H: 1 I: 8 L: 8 K: 10 M: 3 F: 2 P: 3 S: 3 T: 10 W: 1 Y: 2 V: 4
Chemical Descriptors
97 reviewed residue count
C477H771N129O162S4 sequence-only estimate (linear, free termini)
11033.38 sequence-only estimate (linear, free termini)
4.38 sequence-only estimate (linear, free termini)
-7 sequence-only estimate (linear, free termini)
2.56 sequence-only estimate (linear, free termini)
-0.760 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Inhibits E. coli and M. luteus. No MIC. Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Inhibits E. coli and M. luteus. No MIC. Updated 7/2021