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Peptide record

TPDB23385

Antibacterial standard
48 amino acids
Basic Information
3D PDB MODEL
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TPDB23385
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 48-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
MATFLRIVAQLSSKAAKWALDNKDKVLKWIRDGMAIDWIIDKINDIVG
Physicochemical Analysis
C250H406N66O67S2
CEHPY
I
5472.50
9.96
8
6
26
+2
4.42
0.146
120.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
16500
301.51
6
Residue Composition
number
6
A
2
R
2
N
6
D
0
C
0
E
1
Q
2
G
0
H
7
I
4
L
6
K
2
M
1
F
0
P
2
S
1
T
3
W
0
Y
3
V
Amino Acid Distribution
A: 6 R: 2 N: 2 D: 6 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 7 L: 4 K: 6 M: 2 F: 1 P: 0 S: 2 T: 1 W: 3 Y: 0 V: 3
Chemical Descriptors
48
C250H406N66O67S2
5472.50
9.96
+2
4.42
0.146
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.585 µM

Target

G. lituanicus DSM 15325T

Source & Reference

NA

Other

active mostly against thermophilic bacteria. Active against G. lituanicus DSM 15325T (MIC 0.585 uM), G. kaustophilus HTA 426 (MIC 0.293 uM), G. thermodenitrificans DSM 465T (MIC 2.34 uM), G
Evidence 2 Activity

Activity

MIC
Antibacterial
0.293 µM

Target

G. kaustophilus HTA 426

Source & Reference

NA

Other

ly against thermophilic bacteria. Active against G. lituanicus DSM 15325T (MIC 0.585 uM), G. kaustophilus HTA 426 (MIC 0.293 uM), G. thermodenitrificans DSM 465T (MIC 2.34 uM), G. thermoleovorans DSM 5366T (MIC 0.585 u
Evidence 3 Activity

Activity

MIC
Antibacterial
2.34 µM

Target

G. thermodenitrificans DSM 465T

Source & Reference

NA

Other

against G. lituanicus DSM 15325T (MIC 0.585 uM), G. kaustophilus HTA 426 (MIC 0.293 uM), G. thermodenitrificans DSM 465T (MIC 2.34 uM), G. thermoleovorans DSM 5366T (MIC 0.585 uM), and P. toebii DSM 14590T (MIC 4.45 uM). In
Evidence 4 Activity

Activity

MIC
Antibacterial
0.585 µM

Target

G. thermoleovorans DSM 5366T

Source & Reference

NA

Other

), G. kaustophilus HTA 426 (MIC 0.293 uM), G. thermodenitrificans DSM 465T (MIC 2.34 uM), G. thermoleovorans DSM 5366T (MIC 0.585 uM), and P. toebii DSM 14590T (MIC 4.45 uM). In addition, spot on a lawn assay at 55oC: growt
Evidence 5 Activity

Activity

MIC
Antibacterial
4.45 µM

Target

P. toebii DSM 14590T

Source & Reference

NA

Other

rmodenitrificans DSM 465T (MIC 2.34 uM), G. thermoleovorans DSM 5366T (MIC 0.585 uM), and P. toebii DSM 14590T (MIC 4.45 uM). In addition, spot on a lawn assay at 55oC: growth inhibition: A. pallidus DSM 3670T (+++