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Peptide record

TPDB23344

Antibacterial standard
90 amino acids
Basic Information
3D PDB MODEL
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TPDB23344
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 90-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
MANKAELIDVASKTGLTKKDATSAVDAVFETIQENLSEGNKVQLIGFGNFEVRQRAARKGRNPQTGEEIKIPASKVPAFKPGKALKDSVK
Physicochemical Analysis
C425H707N123O132S1
CHWY
K
9684.09
10.23
16
11
33
+5
31.34
-0.530
78.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
19
Residue Composition
number
11
A
4
R
5
N
4
D
0
C
7
E
4
Q
7
G
0
H
5
I
5
L
12
K
1
M
4
F
4
P
5
S
5
T
0
W
0
Y
7
V
Amino Acid Distribution
A: 11 R: 4 N: 5 D: 4 C: 0 E: 7 Q: 4 G: 7 H: 0 I: 5 L: 5 K: 12 M: 1 F: 4 P: 4 S: 5 T: 5 W: 0 Y: 0 V: 7
Chemical Descriptors
90
C425H707N123O132S1
9684.09
10.23
+5
31.34
-0.530
Evidence Records 1 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Diffusion zone assay: active against Gram+ S. aureus ATCC 29213, 25923 (23.1-24.4 mm), E. faecalis ATCC 29212 (12.9 mm), L. monocytogenes CMCC 54004 (21.7 mm), resistant S. aureus 1 (13.2 mm), 3 (10.6 mm) and 4 (11.6), Gram- E. coli ATCC 25922 (20.9 mm), Salmonella CMCC 50071 (27.3 mm), C. sakazakii ATCC 29544 (22.7 mm), also active against antibiotic-resistant C. sakazakii (21.5-23.5 mm) and Salmonella 557D (22 mm). In addition, the MIC of this peptide was measured to be 13.7 ug/ml against S. aureus ATCC 29213 and E. coli ATCC 25922. Reg. 11/2021