Peptide record

TPDB23306

Antibacterial Antiviral Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB23306
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
MAILGDTAWDFGSLGGVFTSIGKALHQVFGAIY
Physicochemical Analysis
C161H240N38O44S1
RNCEP
G
3443.96
5.10
2
2
18
-1
-3.97
0.776
100.61
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
202.96
6
Residue Composition
number
4
A
0
R
0
N
2
D
0
C
0
E
1
Q
6
G
1
H
3
I
3
L
1
K
1
M
3
F
0
P
2
S
2
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 2 C: 0 E: 0 Q: 1 G: 6 H: 1 I: 3 L: 3 K: 1 M: 1 F: 3 P: 0 S: 2 T: 2 W: 1 Y: 1 V: 2
Chemical Descriptors
33
C161H240N38O44S1
3443.96
5.10
-1
-3.97
0.776
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
Release of dengue virus genome induced by a peptide inhibitor. | PLoS One | 2012
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Baby Hamster Kidney cells BHK-21

Target

Baby Hamster Kidney cells BHK-21

Source & Reference

NA
DBAASP
Release of dengue virus genome induced by a peptide inhibitor. | PLoS One | 2012
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.31351847]No cytotoxicity against LLCMK-2 monkey kidney epithelial cells at 100 mg/ml.

Source & Reference

NA
DRAMP
Bioorg Med Chem. 2019 Sep 15 27(18):3963-3978.