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Peptide record

TPDB23268

Antibacterial Antifungal standard
51 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB23268
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 51-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
MAFPFSTQRINPEIEEGNASLADLPVTHAGSLPGIKAQVRTALGIALLLVA
Physicochemical Analysis
C238H390N64O70S1
CWY
A
5300.16
5.43
4
4
25
-1
6.71
0.441
116.86
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
10
Residue Composition
number
8
A
2
R
2
N
1
D
0
C
3
E
2
Q
4
G
1
H
4
I
7
L
1
K
1
M
2
F
4
P
3
S
3
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 8 R: 2 N: 2 D: 1 C: 0 E: 3 Q: 2 G: 4 H: 1 I: 4 L: 7 K: 1 M: 1 F: 2 P: 4 S: 3 T: 3 W: 0 Y: 0 V: 3
Chemical Descriptors
51
C238H390N64O70S1
5300.16
5.43
-1
6.71
0.441
Evidence Records 24 records
Evidence 1 Activity

Activity

MIC
Antibacterial
9.38 µg/mL

Target

Escherichia coli strains

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli strains (MIC 9.38 ug/ml) or >200 ug/mL, S. dysenteriae (MIC 9.38 ug/ml), K. Pneumoniae (MIC 37.5 ug/ml (or >200 ug
Evidence 2 Activity

Activity

MIC
Antibacterial
9.38 µg/mL

Target

S. dysenteriae

Source & Reference

dbAMP

Other

Active against E. coli strains (MIC 9.38 ug/ml) or >200 ug/mL, S. dysenteriae (MIC 9.38 ug/ml), K. Pneumoniae (MIC 37.5 ug/ml (or >200 ug/mL, A. baumannii (MIC 75 ug/ml) or >200 ug/mL,
Evidence 3 Activity

Activity

MIC
Antibacterial
75 µg/mL

Target

A. baumannii

Source & Reference

dbAMP

Other

200 ug/mL, S. dysenteriae (MIC 9.38 ug/ml), K. Pneumoniae (MIC 37.5 ug/ml (or >200 ug/mL, A. baumannii (MIC 75 ug/ml) or >200 ug/mL, S. maltophilia (MIC 18.75 ug/mL), A. baumannii (MIC 75 ug/mL), S. aureus s
Evidence 4 Activity

Activity

MIC
Antibacterial
18.75 ug/mL

Target

Stenotrophomonas maltophilia

Source & Reference

dbAMP

Other

K. Pneumoniae (MIC 37.5 ug/ml (or >200 ug/mL, A. baumannii (MIC 75 ug/ml) or >200 ug/mL, S. maltophilia (MIC 18.75 ug/mL), A. baumannii (MIC 75 ug/mL), S. aureus strains (MIC 18.75 ug/ml) or >200 ug/mL, B. subti
Evidence 5 Activity

Activity

MIC
Antibacterial
75 ug/mL

Target

A. baumannii

Source & Reference

dbAMP

Other

>200 ug/mL, A. baumannii (MIC 75 ug/ml) or >200 ug/mL, S. maltophilia (MIC 18.75 ug/mL), A. baumannii (MIC 75 ug/mL), S. aureus strains (MIC 18.75 ug/ml) or >200 ug/mL, B. subtilis (MIC 9.38 ug/mL), E. faec
Evidence 6 Activity

Activity

MIC
Antibacterial
18.75 µg/mL

Target

Staphylococcus aureus strains

Source & Reference

dbAMP

Other

C 75 ug/ml) or >200 ug/mL, S. maltophilia (MIC 18.75 ug/mL), A. baumannii (MIC 75 ug/mL), S. aureus strains (MIC 18.75 ug/ml) or >200 ug/mL, B. subtilis (MIC 9.38 ug/mL), E. faecium (MIC 4.69 ug/mL), N. asteroides (
Evidence 7 Activity

Activity

MIC
Antibacterial
9.38 ug/mL

Target

B. subtilis

Source & Reference

dbAMP

Other

5 ug/mL), A. baumannii (MIC 75 ug/mL), S. aureus strains (MIC 18.75 ug/ml) or >200 ug/mL, B. subtilis (MIC 9.38 ug/mL), E. faecium (MIC 4.69 ug/mL), N. asteroides (MIC 37.5 ug/mL), fungi C. albicans (MIC 37.5
Evidence 8 Activity

Activity

MIC
Antibacterial
4.69 ug/mL

Target

E. faecium

Source & Reference

dbAMP

Other

ug/mL), S. aureus strains (MIC 18.75 ug/ml) or >200 ug/mL, B. subtilis (MIC 9.38 ug/mL), E. faecium (MIC 4.69 ug/mL), N. asteroides (MIC 37.5 ug/mL), fungi C. albicans (MIC 37.5 ug/ml) or >200 ug/mL, aquati
Evidence 9 Activity

Activity

MIC
Antibacterial
37.5 ug/mL

Target

N. asteroides

Source & Reference

dbAMP

Other

IC 18.75 ug/ml) or >200 ug/mL, B. subtilis (MIC 9.38 ug/mL), E. faecium (MIC 4.69 ug/mL), N. asteroides (MIC 37.5 ug/mL), fungi C. albicans (MIC 37.5 ug/ml) or >200 ug/mL, aquatic pathogens V. brasiliensis (MIC
Evidence 10 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

Candida albicans

Source & Reference

dbAMP

Other

ilis (MIC 9.38 ug/mL), E. faecium (MIC 4.69 ug/mL), N. asteroides (MIC 37.5 ug/mL), fungi C. albicans (MIC 37.5 ug/ml) or >200 ug/mL, aquatic pathogens V. brasiliensis (MIC 75 ug/mL), and E. tarda (MIC 37.5 u
Evidence 11 Activity

Activity

MIC
Antibacterial
75 ug/mL

Target

V. brasiliensis

Source & Reference

dbAMP

Other

des (MIC 37.5 ug/mL), fungi C. albicans (MIC 37.5 ug/ml) or >200 ug/mL, aquatic pathogens V. brasiliensis (MIC 75 ug/mL), and E. tarda (MIC 37.5 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

E. tarda

Source & Reference

dbAMP

Other

ans (MIC 37.5 ug/ml) or >200 ug/mL, aquatic pathogens V. brasiliensis (MIC 75 ug/mL), and E. tarda (MIC 37.5 ug/ml). Updated 7/2021
Evidence 13 Activity

Activity

MIC
Antifungal
9.38 µg/mL

Target

Escherichia coli strains

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli strains (MIC 9.38 ug/ml) or >200 ug/mL, S. dysenteriae (MIC 9.38 ug/ml), K. Pneumoniae (MIC 37.5 ug/ml (or >200 ug
Evidence 14 Activity

Activity

MIC
Antifungal
9.38 µg/mL

Target

S. dysenteriae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli strains (MIC 9.38 ug/ml) or >200 ug/mL, S. dysenteriae (MIC 9.38 ug/ml), K. Pneumoniae (MIC 37.5 ug/ml (or >200 ug/mL, A. baumannii (MIC 75 ug/ml) or >200 ug/mL,
Evidence 15 Activity

Activity

MIC
Antifungal
75 µg/mL

Target

A. baumannii

Source & Reference

dbAMP CAFPdb Antifungipept

Other

200 ug/mL, S. dysenteriae (MIC 9.38 ug/ml), K. Pneumoniae (MIC 37.5 ug/ml (or >200 ug/mL, A. baumannii (MIC 75 ug/ml) or >200 ug/mL, S. maltophilia (MIC 18.75 ug/mL), A. baumannii (MIC 75 ug/mL), S. aureus s
Evidence 16 Activity

Activity

MIC
Antifungal
18.75 ug/mL

Target

Stenotrophomonas maltophilia

Source & Reference

dbAMP CAFPdb Antifungipept

Other

K. Pneumoniae (MIC 37.5 ug/ml (or >200 ug/mL, A. baumannii (MIC 75 ug/ml) or >200 ug/mL, S. maltophilia (MIC 18.75 ug/mL), A. baumannii (MIC 75 ug/mL), S. aureus strains (MIC 18.75 ug/ml) or >200 ug/mL, B. subti
Evidence 17 Activity

Activity

MIC
Antifungal
75 ug/mL

Target

A. baumannii

Source & Reference

dbAMP CAFPdb Antifungipept

Other

>200 ug/mL, A. baumannii (MIC 75 ug/ml) or >200 ug/mL, S. maltophilia (MIC 18.75 ug/mL), A. baumannii (MIC 75 ug/mL), S. aureus strains (MIC 18.75 ug/ml) or >200 ug/mL, B. subtilis (MIC 9.38 ug/mL), E. faec
Evidence 18 Activity

Activity

MIC
Antifungal
18.75 µg/mL

Target

Staphylococcus aureus strains

Source & Reference

dbAMP CAFPdb Antifungipept

Other

C 75 ug/ml) or >200 ug/mL, S. maltophilia (MIC 18.75 ug/mL), A. baumannii (MIC 75 ug/mL), S. aureus strains (MIC 18.75 ug/ml) or >200 ug/mL, B. subtilis (MIC 9.38 ug/mL), E. faecium (MIC 4.69 ug/mL), N. asteroides (
Evidence 19 Activity

Activity

MIC
Antifungal
9.38 ug/mL

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

5 ug/mL), A. baumannii (MIC 75 ug/mL), S. aureus strains (MIC 18.75 ug/ml) or >200 ug/mL, B. subtilis (MIC 9.38 ug/mL), E. faecium (MIC 4.69 ug/mL), N. asteroides (MIC 37.5 ug/mL), fungi C. albicans (MIC 37.5
Evidence 20 Activity

Activity

MIC
Antifungal
4.69 ug/mL

Target

E. faecium

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/mL), S. aureus strains (MIC 18.75 ug/ml) or >200 ug/mL, B. subtilis (MIC 9.38 ug/mL), E. faecium (MIC 4.69 ug/mL), N. asteroides (MIC 37.5 ug/mL), fungi C. albicans (MIC 37.5 ug/ml) or >200 ug/mL, aquati
Evidence 21 Activity

Activity

MIC
Antifungal
37.5 ug/mL

Target

N. asteroides

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IC 18.75 ug/ml) or >200 ug/mL, B. subtilis (MIC 9.38 ug/mL), E. faecium (MIC 4.69 ug/mL), N. asteroides (MIC 37.5 ug/mL), fungi C. albicans (MIC 37.5 ug/ml) or >200 ug/mL, aquatic pathogens V. brasiliensis (MIC
Evidence 22 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ilis (MIC 9.38 ug/mL), E. faecium (MIC 4.69 ug/mL), N. asteroides (MIC 37.5 ug/mL), fungi C. albicans (MIC 37.5 ug/ml) or >200 ug/mL, aquatic pathogens V. brasiliensis (MIC 75 ug/mL), and E. tarda (MIC 37.5 u
Evidence 23 Activity

Activity

MIC
Antifungal
75 ug/mL

Target

V. brasiliensis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

des (MIC 37.5 ug/mL), fungi C. albicans (MIC 37.5 ug/ml) or >200 ug/mL, aquatic pathogens V. brasiliensis (MIC 75 ug/mL), and E. tarda (MIC 37.5 ug/ml). Updated 7/2021
Evidence 24 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

E. tarda

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ans (MIC 37.5 ug/ml) or >200 ug/mL, aquatic pathogens V. brasiliensis (MIC 75 ug/mL), and E. tarda (MIC 37.5 ug/ml). Updated 7/2021