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Peptide record

TPDB23240

Sansalvimide A Antibacterial Anticancer modified_plain modified
5 amino acids
Basic Information
3D PDB MODEL
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TPDB23240
Sansalvimide A
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
Peptipedia CancerPPD 2.0
modified_plain
Yes
A 5-aa modified multi-activity (Antibacterial and Anticancer) peptide sequence curated from Peptipedia and CancerPPD 2.0, with an available 3D structural model.
C-terminal: Cyclized Chemical: X = OLeu N-terminal: Cyclized
Sequence
LXVLF
Physicochemical Analysis
C26H42N4O5
ARNDCEQGHIKMPSTWY
L
490.64
6.02
0
0
4
-0
-2.18
2.920
214.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
5
C26H42N4O5
490.64
6.02
-0
-2.18
2.920
Cyclized
X = OLeu
L
Cyclic
Cyclized
Anticancer
Fusarium sp.
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 9.8 µg/ml
Anticancer
9.8 µg/mL

Target

Colon Cancer
HCT-116
Colon

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 3.5 µg/ml
Anticancer
3.5 µg/mL

Target

Colon Cancer
Colo-205
Colon

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2022
Evidence 3 Activity

Activity

IC50
IC50 = 5.9 µg/ml
Anticancer
5.9 µg/mL

Target

Skin Cancer
SK-MEL-2
Skin

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2022