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Peptide record

TPDB23224

Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB23224
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CAFPdb PD_Hemolysis
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, CAFPdb, and PD_Hemolysis, with an available 3D structural model.
Sequence
LWKIWKKIWRVWKNWR
Physicochemical Analysis
C118H172N32O18
ADCEQGHMFPSTY
W
2326.87
12.44
6
0
9
+6
-4.36
-0.975
91.25
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
27500
1181.85
1
Residue Composition
number
0
A
2
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
4
K
0
M
0
F
0
P
0
S
0
T
5
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 5 Y: 0 V: 1
Chemical Descriptors
16
C118H172N32O18
2326.87
12.44
+6
-4.36
-0.975
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
16 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 16 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel Cecropin-4 Derived Peptides against Methicillin-Resistant Staphylococcus aureus. | Antibiotics (Basel) | 2021
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Antibiotics (Basel). 2021 Jan 1 10(1):37.
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis