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Peptide record

TPDB23168

Antibacterial Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB23168
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 28-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LVDIYTHVYNCTSSEKHTHCYEIRKSIS
Physicochemical Analysis
C145H224N40O46S2
AQGMFPW
S
3327.73
7.25
6
3
9
+0
7.65
-0.514
76.43
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
4595
138.08
13
Residue Composition
number
0
A
1
R
1
N
1
D
2
C
2
E
0
Q
0
G
3
H
3
I
1
L
2
K
0
M
0
F
0
P
4
S
3
T
0
W
3
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 1 C: 2 E: 2 Q: 0 G: 0 H: 3 I: 3 L: 1 K: 2 M: 0 F: 0 P: 0 S: 4 T: 3 W: 0 Y: 3 V: 2
Chemical Descriptors
28
C145H224N40O46S2
3327.73
7.25
+0
7.65
-0.514
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
10.7 µM

Target

C. fangi

Source & Reference

NA

Other

active against C. fangi (MIC 10.7 uM), C. michiganensis (MIC 10.5 uM), X. oryzae pv. oryzae (MIC 10.1 uM), R. solanacearum (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
10.5 µM

Target

C. michiganensis

Source & Reference

NA

Other

active against C. fangi (MIC 10.7 uM), C. michiganensis (MIC 10.5 uM), X. oryzae pv. oryzae (MIC 10.1 uM), R. solanacearum (MIC 8.1 uM), X. oryzae pv. oryzicol
Evidence 3 Activity

Activity

MIC
Antibacterial
10.1 µM

Target

v. oryzae

Source & Reference

NA

Other

active against C. fangi (MIC 10.7 uM), C. michiganensis (MIC 10.5 uM), X. oryzae pv. oryzae (MIC 10.1 uM), R. solanacearum (MIC 8.1 uM), X. oryzae pv. oryzicola (MIC 7.7 uM), and B. subtilis 168
Evidence 4 Activity

Activity

MIC
Antibacterial
8.1 µM

Target

R. solanacearum

Source & Reference

NA

Other

fangi (MIC 10.7 uM), C. michiganensis (MIC 10.5 uM), X. oryzae pv. oryzae (MIC 10.1 uM), R. solanacearum (MIC 8.1 uM), X. oryzae pv. oryzicola (MIC 7.7 uM), and B. subtilis 168 (MIC 8.3 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
7.7 µM

Target

v. oryzicola

Source & Reference

NA

Other

IC 10.5 uM), X. oryzae pv. oryzae (MIC 10.1 uM), R. solanacearum (MIC 8.1 uM), X. oryzae pv. oryzicola (MIC 7.7 uM), and B. subtilis 168 (MIC 8.3 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
8.3 µM

Target

B. subtilis 168

Source & Reference

NA

Other

ae (MIC 10.1 uM), R. solanacearum (MIC 8.1 uM), X. oryzae pv. oryzicola (MIC 7.7 uM), and B. subtilis 168 (MIC 8.3 uM).
Evidence 7 Activity

Activity

0.142% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
0.142% Hemolysis | 32 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Isolation of Antimicrobial Genes from Oryza rufipogon Griff by Using a Bacillus subtilis Expression System with Potential Antimicrobial Activities. | Int J Mol Sci | 2020