Back to search

Peptide record

TPDB23156

Antibacterial Antifungal Toxicity standard
61 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB23156
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 61-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LSVKAFTGIQLRGVCGIEVKARGGPDGSGPDESGPDESLSVKAFTGIQLRGVCGIEVKARG
Physicochemical Analysis
C266H443N79O85S2
NHMWY
G
6172.04
8.28
8
7
20
+1
16.05
-0.064
86.23
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
125
2.03
11
Residue Composition
number
4
A
4
R
0
N
3
D
2
C
4
E
2
Q
12
G
0
H
4
I
4
L
4
K
0
M
2
F
3
P
5
S
2
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 4 R: 4 N: 0 D: 3 C: 2 E: 4 Q: 2 G: 12 H: 0 I: 4 L: 4 K: 4 M: 0 F: 2 P: 3 S: 5 T: 2 W: 0 Y: 0 V: 6
Chemical Descriptors
61
C266H443N79O85S2
6172.04
8.28
+1
16.05
-0.064
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
105.56 µM
Hemolytic Cytotoxic
<5% Hemolysis | 105.56 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design, Dimerization, and Recombinant Production of MCh-AMP1–Derived Peptide in Escherichia coli and Evaluation of Its Antifungal Activity and Cytotoxicity. | Front Fungal Biol | 2021