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Peptide record

TPDB23155

Antibacterial Antifungal Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB23155
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
LSVKAFTGIQLRGVCGIEVKARG
Physicochemical Analysis
C106H184N32O29S1
NDHMPWY
G
2402.88
10.58
4
1
10
+3
3.27
0.487
114.35
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
2
A
2
R
0
N
0
D
1
C
1
E
1
Q
4
G
0
H
2
I
2
L
2
K
0
M
1
F
0
P
1
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 1 E: 1 Q: 1 G: 4 H: 0 I: 2 L: 2 K: 2 M: 0 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
23
C106H184N32O29S1
2402.88
10.58
+3
3.27
0.487
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.66 µM

Target

Candida albicans ATCC 10231

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against C. albicans ATCC 10231 (MIC 6.66 uM), C. glabrata ATCC 90030 (MIC 3.33 uM), C. krusei DSM 70079 (MIC 6.66 uM), A. flavus PFCC
Evidence 2 Activity

Activity

MIC
Antibacterial
3.33 µM

Target

C. glabrata ATCC 90030

Source & Reference

dbAMP

Other

Active against C. albicans ATCC 10231 (MIC 6.66 uM), C. glabrata ATCC 90030 (MIC 3.33 uM), C. krusei DSM 70079 (MIC 6.66 uM), A. flavus PFCC 100 (MIC 13.32 uM), A. niger ATCC 9029
Evidence 3 Activity

Activity

MIC
Antibacterial
6.66 µM

Target

C. krusei DSM 70079

Source & Reference

dbAMP

Other

ctive against C. albicans ATCC 10231 (MIC 6.66 uM), C. glabrata ATCC 90030 (MIC 3.33 uM), C. krusei DSM 70079 (MIC 6.66 uM), A. flavus PFCC 100 (MIC 13.32 uM), A. niger ATCC 9029 (MIC 6.66 uM), and A. fumigatus Af
Evidence 4 Activity

Activity

MIC
Antibacterial
13.32 µM

Target

A. flavus PFCC 100

Source & Reference

dbAMP

Other

1 (MIC 6.66 uM), C. glabrata ATCC 90030 (MIC 3.33 uM), C. krusei DSM 70079 (MIC 6.66 uM), A. flavus PFCC 100 (MIC 13.32 uM), A. niger ATCC 9029 (MIC 6.66 uM), and A. fumigatus Af293 (MIC 6.66 uM). Also provided by
Evidence 5 Activity

Activity

MIC
Antibacterial
6.66 µM

Target

A. niger ATCC 9029

Source & Reference

dbAMP

Other

0030 (MIC 3.33 uM), C. krusei DSM 70079 (MIC 6.66 uM), A. flavus PFCC 100 (MIC 13.32 uM), A. niger ATCC 9029 (MIC 6.66 uM), and A. fumigatus Af293 (MIC 6.66 uM). Also provided by the authors. Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antibacterial
6.66 µM

Target

A. fumigatus Af293

Source & Reference

dbAMP

Other

9 (MIC 6.66 uM), A. flavus PFCC 100 (MIC 13.32 uM), A. niger ATCC 9029 (MIC 6.66 uM), and A. fumigatus Af293 (MIC 6.66 uM). Also provided by the authors. Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antifungal
6.66 µM

Target

Candida albicans ATCC 10231

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against C. albicans ATCC 10231 (MIC 6.66 uM), C. glabrata ATCC 90030 (MIC 3.33 uM), C. krusei DSM 70079 (MIC 6.66 uM), A. flavus PFCC
Evidence 8 Activity

Activity

MIC
Antifungal
3.33 µM

Target

C. glabrata ATCC 90030

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against C. albicans ATCC 10231 (MIC 6.66 uM), C. glabrata ATCC 90030 (MIC 3.33 uM), C. krusei DSM 70079 (MIC 6.66 uM), A. flavus PFCC 100 (MIC 13.32 uM), A. niger ATCC 9029
Evidence 9 Activity

Activity

MIC
Antifungal
6.66 µM

Target

C. krusei DSM 70079

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ctive against C. albicans ATCC 10231 (MIC 6.66 uM), C. glabrata ATCC 90030 (MIC 3.33 uM), C. krusei DSM 70079 (MIC 6.66 uM), A. flavus PFCC 100 (MIC 13.32 uM), A. niger ATCC 9029 (MIC 6.66 uM), and A. fumigatus Af
Evidence 10 Activity

Activity

MIC
Antifungal
13.32 µM

Target

A. flavus PFCC 100

Source & Reference

dbAMP CAFPdb Antifungipept

Other

1 (MIC 6.66 uM), C. glabrata ATCC 90030 (MIC 3.33 uM), C. krusei DSM 70079 (MIC 6.66 uM), A. flavus PFCC 100 (MIC 13.32 uM), A. niger ATCC 9029 (MIC 6.66 uM), and A. fumigatus Af293 (MIC 6.66 uM). Also provided by
Evidence 11 Activity

Activity

MIC
Antifungal
6.66 µM

Target

A. niger ATCC 9029

Source & Reference

dbAMP CAFPdb Antifungipept

Other

0030 (MIC 3.33 uM), C. krusei DSM 70079 (MIC 6.66 uM), A. flavus PFCC 100 (MIC 13.32 uM), A. niger ATCC 9029 (MIC 6.66 uM), and A. fumigatus Af293 (MIC 6.66 uM). Also provided by the authors. Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antifungal
6.66 µM

Target

A. fumigatus Af293

Source & Reference

dbAMP CAFPdb Antifungipept

Other

9 (MIC 6.66 uM), A. flavus PFCC 100 (MIC 13.32 uM), A. niger ATCC 9029 (MIC 6.66 uM), and A. fumigatus Af293 (MIC 6.66 uM). Also provided by the authors. Updated 7/2021
Evidence 13 Activity

Activity

3.65% Hemolysis
Toxicity
13.32 µM
Hemolytic Cytotoxic
3.65% Hemolysis | 13.32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Isolation, functional characterization and biological properties of MCh-AMP1, a novel antifungal peptide from Matricaria chamomilla L. | Chem Biol Drug Des | 2019
Evidence 14 Activity

Activity

10.6% Hemolysis
Toxicity
105.58 µM
Hemolytic Cytotoxic
10.6% Hemolysis | 105.58 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Isolation, functional characterization and biological properties of MCh-AMP1, a novel antifungal peptide from Matricaria chamomilla L. | Chem Biol Drug Des | 2019
Evidence 15 Activity

Activity

10% Cytotoxicity
Toxicity
13.23 µM
Cytotoxic
10% Cytotoxicity | 13.23 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Isolation, functional characterization and biological properties of MCh-AMP1, a novel antifungal peptide from Matricaria chamomilla L. | Chem Biol Drug Des | 2019
Evidence 16 Activity

Activity

23% Cytotoxicity
Toxicity
26.64 µM
Cytotoxic
23% Cytotoxicity | 26.64 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Isolation, functional characterization and biological properties of MCh-AMP1, a novel antifungal peptide from Matricaria chamomilla L. | Chem Biol Drug Des | 2019