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Peptide record

TPDB23144

Apo E Antibacterial Anticancer Antiviral standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB23144
Apo E
Antibacterial Anticancer Antiviral
Anti-infective peptides Cancer-related peptides
Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP dbAMP 3.0 iACP-DRLF pep-lab AI4AVP AVPpred-BWR DRAVP 2.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, and Antiviral) peptide sequence curated from Peptipedia, ACP740 _ACP240, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
LRVRLASHLRKLRKRLLRDADDLQKRLAVY
Physicochemical Analysis
C162H287N57O40
NCEGIMFPTW
L
3673.42
12.03
11
3
14
+7
8.21
-0.610
133.33
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1490
40.56
3
Residue Composition
number
3
A
7
R
0
N
3
D
0
C
0
E
1
Q
0
G
1
H
0
I
8
L
3
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 7 N: 0 D: 3 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 0 L: 8 K: 3 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
30
C162H287N57O40
3673.42
12.03
+7
8.21
-0.610
Free
L
Linear
Free
Antibacterial
Apoprotein E
Evidence Records 5 records
Evidence 1 Activity

Activity

55 % Cytotoxity at 40 µg/ml
Anticancer

Target

Pancreatic Cancer
PANC-1
Pancreatic

Assay & Model

MTT/MTS assay
4-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation. dbAMP 3.0 classified as Anticancer under the disease-associated peptide function classes.
Evidence 2 Activity

Activity

55 % Cytotoxity at 40 µg/ml
Anticancer

Target

Pancreatic Cancer
Paca-2
Pancreatic

Assay & Model

MTT/MTS assay
4-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005
Evidence 3 Activity

Activity

60 % Cytotoxity at 40 µg/ml
Anticancer

Target

Gastric Cancer
MKN-1
Stomach

Assay & Model

MTT/MTS assay
4-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005
Evidence 4 Activity

Activity

35 % Cytotoxity at 40 µg/ml
Anticancer

Target

Gastric Cancer
MKN-7
Stomach

Assay & Model

MTT/MTS assay
4-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005
Evidence 5 Activity

Activity

65 % Cytotoxity at 40 µg/ml
Anticancer

Target

Colon Cancer
COLO-201
Colon

Assay & Model

MTT/MTS assay
4-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005