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Peptide record

TPDB23142

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB23142
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia Antifungipept APD_complete APD_hemolytic Hemolytic2
standard
No
A 36-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, Antifungipept, APD_complete, and other sources, with an available 3D structural model.
Sequence
LSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS
Physicochemical Analysis
C190H312N58O45S6
ADQHMPW
RC
4321.29
10.09
9
1
13
+8
1.21
0.222
81.11
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1865
43.16
12
Residue Composition
number
0
A
6
R
1
N
0
D
6
C
1
E
0
Q
2
G
0
H
2
I
4
L
3
K
0
M
4
F
0
P
2
S
2
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 6 N: 1 D: 0 C: 6 E: 1 Q: 0 G: 2 H: 0 I: 2 L: 4 K: 3 M: 0 F: 4 P: 0 S: 2 T: 2 W: 0 Y: 1 V: 2
Chemical Descriptors
36
C190H312N58O45S6
4321.29
10.09
+8
1.21
0.222
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against E. coli (see ref). Also killed S. aureus based on virtual colony count assays (9.8 ug/ml killed 99.9%). This method exposed bacteria to peptides for 2 h in 10 mM phospahtate buffer before incubating in media for 12 h ( Wang et al., 2023 ). Updated 7/2021, 2/2023
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against E. coli (see ref). Also killed S. aureus based on virtual colony count assays (9.8 ug/ml killed 99.9%). This method exposed bacteria to peptides for 2 h in 10 mM phospahtate buffer before incubating in media for 12 h ( Wang et al., 2023 ). Updated 7/2021, 2/2023
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

NA

Other

Active against E. coli (see ref). Also killed S. aureus based on virtual colony count assays (9.8 ug/ml killed 99.9%). This method exposed bacteria to peptides for 2 h in 10 mM phospahtate buffer before incubating in media for 12 h ( Wang et al., 2023 ). Updated 7/2021, 2/2023
Evidence 4 Activity

Activity

Antiviral

Source & Reference

NA

Other

Active against E. coli (see ref). Also killed S. aureus based on virtual colony count assays (9.8 ug/ml killed 99.9%). This method exposed bacteria to peptides for 2 h in 10 mM phospahtate buffer before incubating in media for 12 h ( Wang et al., 2023 ). Updated 7/2021, 2/2023
Evidence 5 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.