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Peptide record

TPDB23141

Antibacterial Antifungal standard
49 amino acids
Basic Information
3D PDB MODEL
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TPDB23141
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 49-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
LSCRFGRIACIGTCQVQNCGTGYCRGDTCVCSRCGTGGIVGVSVGKKRR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C205H350N72O63S8
EHMPW
G
5087.96
9.03
8
1
12
+7
1.70
0.073
63.47
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1990
0.39
19
Residue Composition
number
1
A
6
R
1
N
1
D
8
C
0
E
2
Q
10
G
0
H
3
I
1
L
2
K
0
M
1
F
0
P
3
S
4
T
0
W
1
Y
5
V
Amino Acid Distribution
A: 1 R: 6 N: 1 D: 1 C: 8 E: 0 Q: 2 G: 10 H: 0 I: 3 L: 1 K: 2 M: 0 F: 1 P: 0 S: 3 T: 4 W: 0 Y: 1 V: 5
Chemical Descriptors
49 reviewed residue count
C205H350N72O63S8 sequence-only estimate (linear, free termini)
5087.96 sequence-only estimate (linear, free termini)
9.03 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
1.70 sequence-only estimate (linear, free termini)
0.073 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

It showed antimicrobial activity against Gram+ S. aureus and S. saprophyticus at low concentrations (0.5–2.5 ug/ml).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

It showed antimicrobial activity against Gram+ S. aureus and S. saprophyticus at low concentrations (0.5–2.5 ug/ml).