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Peptide record

TPDB23120

Antibacterial Antifungal Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB23120
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
standard
No
A 7-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Sequence
LRWLRRL
Physicochemical Analysis
C47H81N17O8
ANDCEQGHIKMFPSTYV
RL
1012.27
12.70
3
0
4
+3
-1.10
-0.429
167.14
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
543.33
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
3
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
7
C47H81N17O8
1012.27
12.70
+3
-1.10
-0.429
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
<10% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Insights into the Mechanism of Antimicrobial Activity of Seven-Residue Peptides. | J Med Chem | 2018
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Insights into the Mechanism of Antimicrobial Activity of Seven-Residue Peptides. | J Med Chem | 2018