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Peptide record

TPDB23085

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB23085
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LRKARRLVKKLA
Physicochemical Analysis
C65H126N24O13
NDCEQGHIMFPSTWY
RLK
1451.87
12.71
6
0
6
+6
3.45
-0.500
138.33
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
3
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C65H126N24O13
1451.87
12.71
+6
3.45
-0.500
Evidence Records 1 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
>2000 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | >2000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Machine learning designs non-hemolytic antimicrobial peptides. | Chem Sci | 2021