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Peptide record

TPDB23072

Antibacterial standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB23072
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 35-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LRDLVCYCRTRGCKRRERMNGTCRRGHLMHTLCCR
Physicochemical Analysis
C169H294N68O45S8
AQIFPSW
R
4255.10
10.40
12
2
8
+8
9.31
-0.791
52.86
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1865
43.83
11
Residue Composition
number
0
A
9
R
1
N
1
D
6
C
1
E
0
Q
3
G
2
H
0
I
4
L
1
K
2
M
0
F
0
P
0
S
3
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 9 N: 1 D: 1 C: 6 E: 1 Q: 0 G: 3 H: 2 I: 0 L: 4 K: 1 M: 2 F: 0 P: 0 S: 0 T: 3 W: 0 Y: 1 V: 1
Chemical Descriptors
35
C169H294N68O45S8
4255.10
10.40
+8
9.31
-0.791
Evidence Records 1 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

killed 99.9% E. coli (4.6 ug/ml) and S. aureus (5.5 ug/ml) based on virtual colony count assays. This method exposed bacteria to peptides for 2 h in 10 mM phospahtate buffer before incubating in media for 12 h.