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Peptide record

TPDB23013

Antibacterial Antifungal Toxicity modified_plain modified
12 amino acids
Basic Information
3D PDB MODEL
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TPDB23013
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 12-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
LNWGAXLKHXXK
Physicochemical Analysis
C50H79N15O11
RDCEQIMFPSTYV
LK
1066.27
10.60
3
0
4
+2
0.23
-0.533
73.33
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
515.82
1
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
2
L
2
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 2 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
12
C50H79N15O11
1066.27
10.60
+2
0.23
-0.533
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Panurgines, novel antimicrobial peptides from the venom of communal bee Panurgus calcaratus (Hymenoptera: Andrenidae). | Amino Acids | 2013
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
40.0 µM
Hemolytic Cytotoxic
50% Hemolysis | 40.0 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Panurgines, novel antimicrobial peptides from the venom of communal bee Panurgus calcaratus (Hymenoptera: Andrenidae). | Amino Acids | 2013
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
43.0 µM
Hemolytic Cytotoxic
50% Hemolysis | 43.0 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Panurgines, novel antimicrobial peptides from the venom of communal bee Panurgus calcaratus (Hymenoptera: Andrenidae). | Amino Acids | 2013