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Peptide record

TPDB23010

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB23010
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LNALKKVFQKIH
Physicochemical Analysis
C68H115N19O15
RDCEGMPSTWY
K
1438.78
10.84
4
0
6
+3
2.27
-0.083
130.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
1
Q
0
G
1
H
1
I
2
L
3
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 1 L: 2 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C68H115N19O15
1438.78
10.84
+3
2.27
-0.083
Evidence Records 1 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
>2000 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | >2000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Machine learning designs non-hemolytic antimicrobial peptides. | Chem Sci | 2021