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Peptide record

TPDB23009

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB23009
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Sequence
LLVLRSLGPWHPGHCLLR
Physicochemical Analysis
C96H155N29O20S1
ANDEQIKMFTY
L
2067.53
10.90
4
0
8
+2
-0.79
0.467
146.11
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
266.02
2
Residue Composition
number
0
A
2
R
0
N
0
D
1
C
0
E
0
Q
2
G
2
H
0
I
6
L
0
K
0
M
0
F
2
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 2 H: 2 I: 0 L: 6 K: 0 M: 0 F: 0 P: 2 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
18
C96H155N29O20S1
2067.53
10.90
+2
-0.79
0.467
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
Fungicidal activity of peptides encoded by immunoglobulin genes. | Sci Rep | 2017
Evidence 2 Activity

Activity

10% Cytotoxicity
Toxicity
250 µM
Cytotoxic
10% Cytotoxicity | 250 | µM | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
Fungicidal activity of peptides encoded by immunoglobulin genes. | Sci Rep | 2017
Evidence 3 Activity

Activity

<10% Hemolysis
Toxicity
500 µM
Hemolytic Cytotoxic
<10% Hemolysis | 500 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Fungicidal activity of peptides encoded by immunoglobulin genes. | Sci Rep | 2017