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Peptide record

TPDB23000

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB23000
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP i2APP APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
LMCTHPLDCSN
Physicochemical Analysis
C49H80N14O17S3
AREQGIKFWYV
CL
1233.44
4.94
1
1
3
-1
1.50
0.109
70.91
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
125
10.13
5
Residue Composition
number
0
A
0
R
1
N
1
D
2
C
0
E
0
Q
0
G
1
H
0
I
2
L
0
K
1
M
0
F
1
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 1 C: 2 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 2 K: 0 M: 1 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C49H80N14O17S3
1233.44
4.94
-1
1.50
0.109
Evidence Records 4 records
Evidence 1 Activity

Activity

Hemolysis
Tn-AFP1 has no adverse effect on red blood cells at concentration of 32 µg mL−1

Source & Reference

Hemolytik APD_complete PD_Hemolysis
DRAMP4
Peptides. 2011 Aug 32(8):1741-1747.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 32 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Identification of an antifungal peptide from Trapa natans fruits with inhibitory effects on Candida tropicalis biofilm formation. | Peptides | 2011
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: Tn-AFP1 has no adverse effect on red blood cells at concentration of 32 µg mL−1

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2011 Aug 32(8):1741-1747.
Evidence 4 Hemolysis

Activity

Tn-AFP1 has no adverse effect on red blood cells at concentration of 32 µg mL−1
Hemolysis

Source & Reference

APD_complete PD_Hemolysis
Peptides. 2011 Aug 32(8):1741-1747.
DRAMP4
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.