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Peptide record

TPDB22999

Antibacterial Antiviral Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB22999
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia dbAMP 3.0 DRAVP 2.0
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, dbAMP 3.0, and DRAVP 2.0, with an available 3D structural model.
Sequence
LMRIRQMMT
Physicochemical Analysis
C48H90N16O12S3
ANDCEGHKFPSWYV
M
1179.52
12.40
2
0
5
+2
0.78
0.089
86.67
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
1
L
0
K
3
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 1 K: 0 M: 3 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C48H90N16O12S3
1179.52
12.40
+2
0.78
0.089
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>500 µM
Cytotoxic
50% Cell death | >500 | µM | target cell: MARC-145 cells

Target

MARC-145 cells

Source & Reference

NA
DBAASP
Antiviral activity of phage display selected peptides against Porcine reproductive and respiratory syndrome virus in vitro. | Virology | 2012
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.22743126]MARC-145 cells:CC50>500 µM.

Source & Reference

NA
DRAMP
Virology. 2012 Oct 10 432(1):73-80.