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Peptide record

TPDB22949

Antibacterial Toxicity standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB22949
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 6-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LLLLLW
Physicochemical Analysis
C41H67N7O7
ARNDCEQGHIKMFPSTYV
L
770.03
6.02
0
0
6
-0
-4.65
3.017
325.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
714.26
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
6
C41H67N7O7
770.03
6.02
-0
-4.65
3.017
Evidence Records 3 records
Evidence 1 Activity

Activity

14.39 ±0.7% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
14.39 ±0.7% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022
Evidence 2 Activity

Activity

15.13 ± 2.05% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
15.13 ± 2.05% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022
Evidence 3 Activity

Activity

27.97 ±2.79% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
27.97 ±2.79% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022