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Peptide record

TPDB22902

Antibacterial Toxicity standard
54 amino acids
Basic Information
3D PDB MODEL
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TPDB22902
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 54-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTESDYKDDDDKCQDSERTFY
Physicochemical Analysis
C294H465N83O89S1
AHMW
DK
6618.49
9.32
14
12
16
+2
22.62
-1.220
61.30
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
2980
45.03
11
Residue Composition
number
0
A
6
R
1
N
8
D
1
C
4
E
2
Q
2
G
0
H
3
I
4
L
8
K
0
M
5
F
1
P
3
S
2
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 6 N: 1 D: 8 C: 1 E: 4 Q: 2 G: 2 H: 0 I: 3 L: 4 K: 8 M: 0 F: 5 P: 1 S: 3 T: 2 W: 0 Y: 2 V: 2
Chemical Descriptors
54
C294H465N83O89S1
6618.49
9.32
+2
22.62
-1.220
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Collagen tethering of synthetic human antimicrobial peptides cathelicidin LL37 and its effects on antimicrobial activity and cytotoxicity. | Acta Biomater | 2017