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Peptide record

TPDB22834

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB22834
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LKKLWKRIIKVGR
Physicochemical Analysis
C78H140N24O14
ANDCEQHMFPSTY
K
1638.12
12.44
6
0
6
+6
2.07
-0.392
142.31
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
335.75
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
2
L
4
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C78H140N24O14
1638.12
12.44
+6
2.07
-0.392
Evidence Records 1 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
>2000 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | >2000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Machine learning designs non-hemolytic antimicrobial peptides. | Chem Sci | 2021