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Peptide record

TPDB22827

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB22827
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LKKLCRILKKLCRILKKLCRI
Physicochemical Analysis
C117H224N36O22S3
ANDEQGHMFPSTWYV
LK
2583.47
11.14
9
0
9
+9
3.36
0.329
167.14
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
125
4.84
3
Residue Composition
number
0
A
3
R
0
N
0
D
3
C
0
E
0
Q
0
G
0
H
3
I
6
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 3 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 6 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C117H224N36O22S3
2583.47
11.14
+9
3.36
0.329
Evidence Records 1 records
Evidence 1 Activity

Activity

18% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
18% Hemolysis | 64 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
The antimicrobial peptide LI14 combats multidrug-resistant bacterial infections. | Commun Biol | 2022