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Peptide record

TPDB22808

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB22808
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LKKACRILKKLCRI
Physicochemical Analysis
C75H144N24O15S2
NDEQGHMFPSTWYV
K
1686.24
10.97
6
0
6
+6
2.63
0.186
146.43
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
125
7.41
2
Residue Composition
number
1
A
2
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
2
I
3
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 3 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C75H144N24O15S2
1686.24
10.97
+6
2.63
0.186
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 128 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
The antimicrobial peptide LI14 combats multidrug-resistant bacterial infections. | Commun Biol | 2022