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Peptide record

TPDB22772

Antibacterial Toxicity modified_plain modified
21 amino acids
Basic Information
3D PDB MODEL
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TPDB22772
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 21-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
LIAGLAANFLPQILXKIARKC
Physicochemical Analysis
C100H173N27O23S1
DEHMSTWYV
AL
2153.70
10.59
3
0
12
+3
-0.97
0.948
149.05
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
4
A
1
R
1
N
0
D
1
C
0
E
1
Q
1
G
0
H
3
I
4
L
2
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 1 N: 1 D: 0 C: 1 E: 0 Q: 1 G: 1 H: 0 I: 3 L: 4 K: 2 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C100H173N27O23S1
2153.70
10.59
+3
-0.97
0.948
Evidence Records 1 records
Evidence 1 Activity

Activity

25% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-Activity Relationship and Mode of Action of a Frog Secreted Antibacterial Peptide B1CTcu5 Using Synthetically and Modularly Modified or Deleted (SMMD) Peptides. | PLoS One | 2015